Katare RG, Caporali A et al. Vitamin B1 analogue benfotaimine prevents diabetes-induced diabetolic dysfunction and heart failure through Akt/Pim-1 mediated survival pathway: Circulation:Heart Failure 2010;doi:10.1161/CIRCHEARTFAILURE.10909…

Guo T, Jou W et al. Myostatin inhibition in muscle, but not adipose tissue, decreases fat mass and improves insulin sensitivity. PLoS One 2009;4(3):e4937 myostatin(Mstn)の無いマウスは劇的に筋肉が増し、脂肪が減る。その受容体のactivin受容体Ⅱ…

Chen J, Fontes G et al. Lack of TXNIP protects against mitochondria-mediated apoptosis but not against fatty acid-induced ER stress-mediated β-cell death. Diabetes 2010;59(2):440-447 Txnipはチオレドキシンを抑制して酸化ストレスを悪化させる…

Hamaguchi E, Takamura T et al. Histological course of nonalcoholic fatty lover disease in Japanese patients. Tight glycemic control, rather than weight reduction, ameliorates liver fibrosis. Diabetes Care 2010;33(2):284-6 非アルコール性脂…

Cleveringa FGW, Welsing PMJ et al. Cost-effectiveness of the Diabetes Care Protocol, a multifaceted computerized decision support diabetes management intervention that reduces cardiovascular risk. Diabetes Care 2010;33(2):258-263 糖尿病患…

Kamada Y, Yoshino K et al. Tor directly controlsthe Atg1 kinase complex to regulate autophagy. Mol Cell Biol 2010;30(4):1049-1058 栄養障害→TORC1（タンパクキナーゼの複合体）の不活性化→Atg13のセリンリン酸化の低下→Atg1キナーゼ複合体の活性化→a…